irssi
Used by 18 peopleirssi.org ↗

“I'm logged into IRC 24x7, using irssi in a screen session, an approach I've been using for over ten years.”
Brendan Gregg Interview, Senior performance architect (Netflix) · via Uses This 
“As a Technical Architect within a large team I don't get to do serious coding any more - my time is variously split between meetings with engineers & product people, email generation, IRC (irssi) and working up specifications and approaches for things, which can then be iterated on.”
Paul Tweedy Interview, Senior Technical Architect, BBC · via Uses This
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