mIRC
Used by 4 peoplemirc.com ↗

“I don't bother with Twitter, email, or IM (other than Skype), but I use mIRC for IRC.”
David Cramer Interview, Developer, infrastructure nerd (DISQUS) · via Uses This 
“For IRC, I'm nostalgic for the customizability of mIRC.”
Matt Might Interview, CS Professor (University of Utah) · via Uses This